Kenya Medical Laboratory Tests

Thrombin time Test in Kenya

Brief Description

This test is used to evaluate the activity of fibrinogen in coagulation. Thrombin is the enzyme that acts on fibrinogen in the blood resulting in the formation of fibrin threads that helps form a clot at the site of injury. Thrombin clotting time is"," therefore"," the duration of fibrin clot formation after addition of thrombin to citrated plasma.


Thrombin clotting time (TCT)

Patient Preparation

The patient should ideally not be on anticoagulation therapy at the time of testing"," but should consult with the physician before the test.

Sample Type

Citrated plasma

Sample volume

1 mL

Sample collection Container

Sodium citrate tube (blue top)

Sample collection instructions

Sample should be collected in a 3.2% buffered sodium citrate tube and mixed gently immediately after to ensure adequate mixing of the blood with the anticoagulant. The sample should be centrifuged for 10 minutes and 2/3 of the plasma carefully separated and kept frozen until testing.

Sample storage

Keep frozen at 40c

Reference range

12-19 seconds

Results Turnaround

1-2 days

Diseases / Diagnostic Indicators

Insufficient fibrinogen abnormal fibrinogen function may be indicated by a prolonged thrombin time. It can also result from illnesses including end-stage liver disease"," malnutrition"," as well as conditions that limit fibrin formation"," such as disseminated intravascular coagulation (DIC) and abn